Transfer of specific antibodies results in increased expression of TNF-alpha and IL12 and recruitment of neutrophils to the site of a cutaneous Francisella tularensis infection.
نویسندگان
چکیده
This study demonstrates that passive transfer of Francisella tularensis-specific antibodies before experimental cutaneous infection with the live vaccine strain of F. tularensis has profound effects. Recipient mice showed stronger staining for TNF-alpha and IL12, and larger numbers of neutrophils in skin samples after infection than control mice.
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عنوان ژورنال:
- Journal of medical microbiology
دوره 53 Pt 6 شماره
صفحات -
تاریخ انتشار 2004